Across
- 1. Loss of this leads to cancer: cell cycle ___
- 3. Age-related accumulation of cellular damage
- 6. Key factor in both aging and cancer: DNA ___
- 8. Genes that promote uncontrolled cell growth
- 13. Enzyme that elongates telomeres
- 15. Tumor suppressor gene mutated in most cancers
Down
- 2. Damage from reactive oxygen species
- 4. Age-related shortening of replicative potential
- 5. Proteins that suppress tumors
- 7. Uncontrolled multiplication of cells
- 9. Common hallmark of cancer
- 10. Genetic alterations increasing cancer risk
- 11. Shortened protective ends of chromosomes
- 12. Process maintaining DNA integrity
- 14. Programmed cell death