Across
- 2. a PARP inhibitor effective in treating patients with PALB2 mutations
- 3. also known as hereditary non-polyposis colorectal cancer (HNPCC)
- 7. Otherwise known as Human Epidermal Growth Factor Receptor 2
- 8. a sporadic cancer not inherited changes that are acquired during a person's lifetime and are present only in the melanocytes
- 9. MDT team member who manages handling drugs, including the supply of drugs of addiction and restricted substances.
- 10. Inheritance when both parents are unaffected genetic carriers for the condition
- 12. type of cancer mutation synonymous with Angelia Jolie
- 13. Variant that arise during natural cellular processes, such as cell growth and division
- 14. an autosomal dominant inherited condition in which numerous adenomatous polyps form mainly in the epithelium of the large intestine.
Down
- 1. scoring system for cancer risk
- 4. Variant present in the gamete
- 5. There is evidence to suggest that .... increases the risk of second primary cancers in affected carriers of constitutional (germline) TP53.
- 6. Risk reducing surgery for breast cancer
- 11. Variant absent in the gamete