Cancer Genetics - BIOL2301

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Across
  1. 2. _______ and Bacteria are estimated to cause around 18% of all cancer cases.
  2. 5. Technology that is used in cancer research to create model tumors for drug testing.
  3. 7. A ________ maps the record of descent from generation to generation and is used in cancer risk assessments.
  4. 8. The ________ is related to 80% of cancers.
  5. 9. Type of genetic testing that consumers can order and get results for without involving a healthcare provider, for short.
  6. 10. Vaccine type that is efficient in inducing immune responses against cancer.
  7. 13. Causes early aging of the skin through the destruction of collagen and elastin, which can cause cancer.
  8. 14. Disease that occurs when cells in the body grow and divide uncontrollably and can invade other parts of the body.
  9. 15. A mutated gene that can cause cancer.
  10. 16. Low risk variants that associated with cancer risks, for short.
  11. 19. The study of how environmental factors can alter a genes function but not the DNA sequence
  12. 20. They shorten with age, which can cause increases in tumor cells through chromosome fusion.
  13. 22. Type of medicine that is tailored specifically to a patient and their cancer.
Down
  1. 1. Type of genetic testing that looks for inherited gene mutations that can increase the risk of developing cancers.
  2. 3. ________ modifications are vital in the maintenance of genomic stability, and any errors can increase the likelihood of developing cancer.
  3. 4. Type of gene mutation that is passed down from parent to offspring; cause of a small proportion of cancers, but creates a high risk for individuals who have the mutation.
  4. 6. Occurs when a single base pair in a genetic sequence is changed via insertion or deletion.
  5. 11. 3D tissues which capture the essential functions and characteristics of actual organs; created through in vitro stem cell culture.
  6. 12. These are meant to detect and stop damaged cells from continuing through the cell cycle, but when they fail, damaged cells can continue to divide uncontrollably.
  7. 17. P53 is a a protein that regulates ______ and has a mutation in half of all human cancers.
  8. 18. ___________ analysis is used to compare the expression of genes in entire genomes, and is helpful to identify active genes cancerous cells.
  9. 21. _______ rates for cancer are lower for non-white ethnicities.