Across
- 3. Valve deformity caused by immune-mediated commissural fusion (1 word)
- 4. Polysaccharide enhancing colonization on platelet-fibrin layers (1 word)
- 7. Pathogen capable of invading intact endothelium, causing the most rapid valve destruction (2 words)
- 9. Painful immune-complex cutaneous lesions in subacute IE (2 words)
- 11. Microbial motifs (e.g., LPS, lipoteichoic acid) recognized by TLRs (1 word)
- 12. Slow-growing Gram-negative bacilli group requiring CO₂-rich conditions (1 word)
- 13. Spirochete causing fluctuating AV block during Lyme carditis (2 words)
- 14. Surface molecules enabling pathogens to bind matrix proteins like fibronectin and collagen (1 word)
- 16. Structure requiring endothelial micro-ulceration before colonization can occur (1 word)
- 18. Pain of pericarditis due to irritation of parietal pericardial somatic fibers (3 words)
- 19. Agent of culture-negative IE; survives inside acidified phagolysosomes (2 words)
Down
- 1. Microembolic erythematous macules found on palms and soles (2 words)
- 2. Gram-negative rod driving septic shock via massive TNF-α/IL-1 surge (2 words)
- 5. Oral flora species whose extracellular polysaccharides aid adhesion to fibrin-platelet deposits (2 words)
- 6. Bacterium whose exotoxin blocks EF-2, leading to myocarditis (2 words)
- 8. Enterovirus that uses the CAR receptor to enter cardiomyocytes (1 word)
- 10. Autoimmune disease where antibodies cross-react with cardiac myosin and laminin (2 words)
- 15. Multilayered microbial barrier reducing antimicrobial penetration on prosthetic valves (1 word)
- 17. Valve infection begins when this normally non-thrombogenic surface loses integrity (1 word)