CARDIOVASCULAR SYSTEM

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Across
  1. 5. I inhibit cardiac myosin rather than calcium channels, am used in obstructive HCM
  2. 7. I target PCSK9 to produce powerful ldl reduction
  3. 11. I am siRNA but don’t target ldl directly , I target APOC3 and reduce triglycerides
  4. 12. Newly approved endothelin receptor blocker for systemic HTN
  5. 13. DOC for hyper cholesterolemia in pregnancy
Down
  1. 1. Guanyl cyclase stimulator used for CHF
  2. 2. add on drug to statins which inhibits ATP citrate lyase
  3. 3. A patient suddenly develops PSVT at home instead of an iv injection this newer drug can be self administered through nose
  4. 4. Nitrate that does not develop tolerance
  5. 6. Drug restoring normal sinus rhythm in atrial fib with multi channel blockade action
  6. 8. Drug that causes coronary steal syndrome and DLE
  7. 9. aldosterone synthase inhibitor
  8. 10. Newly approved ultra short acting beta blocker