CEDSER

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Across
  1. 2. to bring to an end
  2. 3. related to the heart
  3. 4. science of flying aircraft
  4. 6. business involving farming
Down
  1. 1. human-centered
  2. 3. relating to the body
  3. 5. opposite of friends (root contrast)
  4. 7. to reshape or change