Cell Adaptations

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Across
  1. 2. Shrinkage in the size of the cell by the loss of cell substance; results from decreased protein synthesis and increased protein degradation in cells.
  2. 4. This occurs when cells encounter physiologic stresses or pathologic stimuli.
  3. 7. Well-differentiated, poorly differentiated and anaplastic are all forms of....? (2 words)
  4. 9. An increase in the size of the cells, resulting in an increase in the size of the organ; occurs when cells are incapable of dividing.
  5. 10. The term used for the clinical study of neoplasia.
  6. 11. What term is used to describe tumour cells which develop mutations which allow them to move, grow through a basement membrane and organise the extracellular matrix?
  7. 12. Describes cells which show an increased rate of division, combined with incomplete maturation.
  8. 13. A reversible cellular adaptation to environmental stress in which one adult cell type is replaced by another adult cell type in a different but stable arrangement.
Down
  1. 1. This means 'new growth' and describes cells which have entered the G1 phase of the cell cycle and continue to multiply within the cycle.
  2. 3. What form of adaptation is a response to stress which allows cells to alter their structure and function in order to escape injury?
  3. 5. Characterised by an increase in cell number.
  4. 6. When cells respond to normal stimulation by hormones or endogenous chemical mediators, the adaptations are....?
  5. 8. The term used to describe a decrease in cell numbers.