Cells & Organs of the Immune System

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Across
  1. 5. What type of immunity consists of phagocytosis, complement, interferon, inflammation, and fever
  2. 7. Carrier proteins that present antigens on cell surfaces
  3. 9. Filters lymph by trapping antigens
  4. 13. Identified by expression of CD16 & CD34 when inactive and expression of CD 11b & CD18 when activated
  5. 14. Antibody binds with the pathogen to alert macrophage/neutrophil to engulf/digest
  6. 15. Large encapsulated organ that filters blood, cellular debris, and aged blood cells
  7. 16. Cytotoxic T-cells (CTLs) that kill cancer/infected cell by apoptosis
  8. 18. T-cells and DCs are found in what part of the lymph node
  9. 19. Best known for being the inductive and effector site for intestinal immune response
  10. 20. Where do T-cells mature?
  11. 21. Recognize general microbial patterns and are essential for innate immune cell activation and inflammatory responses
  12. 24. Primary lymphoid organ for B-cell development in ruminants, pigs, dogs, and rabbits
  13. 26. B-cells produce what?
  14. 28. Killer Cells Large Granular Lymphocyte
  15. 29. Cells that monitor and inhibit activity of other T-cells
  16. 30. Which type of selection does thymocytes experience when it can recognize MHC II/Ag complexes with moderate affinity
  17. 33. Antibodies are important for what type of immune response
  18. 34. Cells that coordinate immune responses against extracellular pathogens by alerting B-cells, mast cells, and granulocytes
  19. 35. Important for allergy and inflammation, but also express adhesion molecules in circulation
  20. 36. Antibodies cover the pathogen where it cannot further infect host cells
  21. 39. Small proteins with diverse function
  22. 40. Cells that named for their ability to produce interleukin 17 (IL-17), a signaling molecule that activates immune/non-immune cells
  23. 41. Lymphoid Tissue Where does mature DC go?
  24. 42. T-cells are important for what type of immune response?
Down
  1. 1. Series of proteins in the blood that causes apoptosis, serve as signaling molecules, and recruit themselves to inflammatory sites
  2. 2. Ingests and degrades bacteria
  3. 3. What part of the spleen is where immune induction occurs
  4. 4. Lymphoid cells are first produced in the liver, fetal omentum, and ?
  5. 6. Th refers to
  6. 8. Activation Antibodies directly lyse/destroy the pathogen
  7. 10. Where are B-cells found in birds?
  8. 11. Granulocytes and DC come from what type of progenitor cell
  9. 12. Marrow Where do T-cells originate from?
  10. 17. Similar to Basophils due to CD34+ precursor
  11. 22. Which type of selection does thymocytes go through if the receptor bind strongly to itself
  12. 23. Most numerous innate cell
  13. 25. What type of immunity involves lymphocytes and antibodies
  14. 27. Dendritic Cells What type of cells secrete Type I Interferon upon activation of TLR 7 & TLR 9
  15. 31. immature T-cells
  16. 32. Differentiate in response to IL-3, IL-5, CM-CSF
  17. 37. Which type of progenitor cell differentiates into T-cell, B-cell, and DC
  18. 38. Cells that coordinate immune responses against intracellular pathogens and produce/secrete cytokines to alert/activate other immune cells