Ch 13 Host Defenses 2

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Across
  1. 2. Historical deliberate inoculation of dried smallpox pustule material to induce immunity.
  2. 4. A foreign substance that elicits a specific immune response from a B or T cell.
  3. 6. Small leukocyte with a large round dark nucleus serving as the key player of adaptive immunity.
  4. 7. T cells expressing CD4 co-receptors that recognize antigens via MHC Class II and coordinate immune cells.
  5. 11. Direct administration of pre-formed antibodies conferring immediate but temporary protection without memory.
  6. 12. Inoculation with selected microbial antigens to stimulate primary immunity and memory without disease.
  7. 13. Long-lived lymphocytes formed during primary exposure that record pathogen information for future encounters.
Down
  1. 1. Effector B cells derived from clonal expansion that actively secrete soluble immunoglobulins.
  2. 3. A Y-shaped soluble glycoprotein secreted by plasma cells that binds and marks pathogens for destruction.
  3. 4. A highly specific, memory-based immune defense found only in vertebrates.
  4. 5. T cells expressing CD8 co-receptors that recognize antigens via MHC Class I and directly destroy infected cells.
  5. 8. T cells that modulate the immune response and limit chronic inflammatory damage.
  6. 9. The adaptive defense branch where B cells and secreted antibodies defend against pathogens in body fluids.
  7. 10. The small accessible portion of an antigen that directly binds to an antigen receptor.
  8. 14. Cell-surface host glycoproteins that present processed antigen fragments to T-cell receptors.