Across
- 6. A vasoactive chemical released by mast cell degranulation causing constriction of smooth muscles.
- 7. A chronic localized Type I allergic condition such as hay fever, allergic asthma, or eczema.
- 8. A harmless environmental antigen that induces an exaggerated allergic reaction in sensitive individuals.
- 10. A severe congenital primary immunodeficiency involving the complete absence of functional B and T cells.
- 12. A delayed Type IV cell-mediated allergic skin reaction triggered by contactants like poison ivy.
- 13. An underreactive state where the immune system is incompletely developed, suppressed, or destroyed.
- 14. An overreactive immune state where host tissues are damaged by responses to self or harmless antigens.
- 15. Type II hypersensitivity where IgG or IgM and complement directly lyse targeted cell surfaces.
Down
- 1. Soluble antigen-antibody aggregates that deposit in organ basement membranes in Type III reactions.
- 2. An abnormal situation where the immune system loses self-tolerance and attacks the host's own tissues.
- 3. A severe systemic Type I reaction involving widespread vasodilation and sudden respiratory distress.
- 4. Passive anti-Rh antibodies administered to an Rh-negative mother to prevent maternal sensitization.
- 5. An acquired secondary immunodeficiency caused by HIV destroying helper T cells and macrophages.
- 9. Transplanted tissue or organ transferred from a donor to a recipient host.
- 11. Therapeutic exposure to calculated allergen doses to prevent IgE production by encouraging IgG.