Across
- 5. invertebrates and vertebrates acts rapidly at local and systemic level once first line of defense is overcome
- 10. release antimicrobial peptides
- 12. found on potential pathogens
- 13. "long arms" stimulate the development of adaptive immunity in cells that contact the environment
- 15. circulate through the body and detect abnormal cells
Down
- 1. consists of about 30 proteins that are activated by substances on microbe surfaces
- 2. Vertebrate only, slower response
- 3. discharge destructive enzymes, involved in allergic and anti-helminth responses
- 4. mix of macromolecules on their surface that the immune system senses
- 6. "first responders" circulate in the blood and are attracted by signals from infected tissues
- 7. originate from monocytes
- 8. life-threatening condition caused by an overwhelming inflammatory response
- 9. systemic inflammatory response
- 11. provide innate defense, interfering with viruses and helping activate macrophages
- 14. found on innate immune cells