Chapter 19: Citric Acid Cycle

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Across
  1. 3. Enzyme that catalyzes the isomerization of citrate into isocitrate
  2. 9. Succinate dehydrogenase directly transfers two electrons from FADH2 to ____
  3. 10. Enzyme that catalyzes the one step in the citric acid cycle that generates FADH2
  4. 12. Enzyme that catalyzes the oxidation of malate to form oxaloacetate
  5. 13. The two steps in the citric acid cycle that consume water are catalyzed by ____ and fumarase
  6. 15. A suicide inhibitor or mechnanism-based inhibitor for ___ may lead to an effective treatment for tuberculosis; is an enzyme unique to the glyoxylate cycle
  7. 17. Enzyme that catalyzes the regeneration of oxaloacetate from pyruvate
  8. 18. The two primary control points of the citric acid cycle are isocitrate dehydrogenase and ____
Down
  1. 1. Enzyme that catalyzes the one step in the citric acid cycle that generates ATP
  2. 2. Oxidative decarboxylation of alpha-ketoglutarate forms ____, catalyzed by the alpha-ketoglutarate dehydrogenase complex
  3. 4. ____ cycle allows the conversion of acetyl CoA to glucose, present in plants and some microorganisms
  4. 5. Acetyl CoA condenses with ____ to form citrate, catalyzed by citrate synthase
  5. 6. Enzyme that regulates the activity of transcription factor HIF-1
  6. 7. The three steps in the citric acid cycle that generate NADH are catalyzed by ____, alpha-ketoglutarate dehydrogenase complex, and malate dehydrogenase
  7. 8. Enzyme that catalyzes the hydration of fumarase to form L-malate
  8. 11. Oxidative decarboxylation of isocitrate forms ____, catalyzed by isocitrate dehydrogenase
  9. 14. Oxidation of succinate forms ____, catalyzed by succinate dehydrogenase
  10. 16. Cleavage of the thioester of succinyl CoA forms ____, catalyzed by succinyl CoA synthetase