Chapter 2

1. Organ that initiates adaptive immune response to blood-borne antigens
7. Macrophages lining the sinusoids in the liver (no need to write the word ‘cells’)
8. Cell surface receptor expressed by most helper T cells
10. Event that results in the generation of highly diverse repertoire of antigen specificities
11. Cells whose primary function is to ingest and destroy microbes and remove damaged tissues
15. Lymphocytes in the thymus
16. Center that develops in response to antigenic stimulation and are sites of remarkable B cell proliferation

2. A type of dendritic cell that is found in the epithelial layer of skin
3. These cells become macrophages when they migrate into tissues
4. Circulating antibody secreting cells with features of plasma cells
5. Cells that mediate rapid and enhanced responses to subsequent exposures to antigens (no need to write the word ‘cells’)
6. Substances that coat particles and tag them for phagocytosis
9. Cells that are the most abundant population of white blood cells
12. Organs where the major steps of lymphocyte development occur
13. Nomenclature for naming cell surface molecules characteristic of particular cell lineage (abbreviation)
14. Cells that are the dominant effector cells of the later stages of the innate immune response