Across
- 4. MHC molecule present on all the nucleated cells
- 7. specialized proteins that display host-cell associated antigens to T lymphocytes
- 10. Dendritic cells that are efficient at recognizing and capturing protein antigens
- 12. protein that is critical in the rate of transcription of the MHC molecules
- 13. antigens that are required in the absence of infection for optimal T cell response to purified protein antigens
- 14. the membrane-bound molecules of APCs that function together with antigen to stimulate T cells
- 15. cells that capture antigens and display them to T lymphocytes (no need to mention ‘cells’)
Down
- 1. associated protein bound to Class II MHC molecules during its synthesis in the ER
- 2. Cells presenting peptide-MHC complexes to maturing T cells in the thymus (no need to mention ‘cells’)
- 3. type of antigen displayed by APCs for the recognition by T lymphocytes
- 5. organ that captures blood-borne antigens
- 6. t cells that are activated by dendritic cells but not by macrophages or B cells
- 8. process that gives the ability to DCs to capture ans ingest virus-infected cells and present the viral antigens to naïve CD8+ T cells
- 9. phenomenon that a single T cell can recognize a specific peptide displayed by only one of the large number of different MHC molecules
- 11. the principle cytokine involved in stimulating the expression of class II molecules in APCs such as DCs