Across
- 3. a substance that reduces the activity of an enzyme by binding to a location remote from the active site, changing the enzyme's shape so that the active site no longer effectively catalyze the conversion of substrate to product
- 4. a temporary complex formed when an enzyme binds to its substrate molecule(s)
- 8. the amount of energy that reactants must absorb before a chemical reaction will start; also called free energy of activation
- 10. a process by which a chemical agent called a catalyst to selectively increases the rate of a reaction without being consumed by the reaction
- 11. the binding of a regulatory molecule to a protein at one site that affects the function of the protein at a different site
- 12. caused by entry of the substrate, the change in shape of the active site of an enzyme so that it binds more snugly to the substrate
- 13. an organic molecule serving as a cofactor. Most vitamins function as coenzymes in the metabolic reactions
Down
- 1. a substance that reduces the activity of an enzyme by entering the active site in place of the substrate, whose structure it mimics
- 2. a method of metabolic control in which the end product of a metabolic pathway acts as an inhibitor of an enzyme within that pathway
- 5. the specific region of an enzyme that binds to the substrate and that forms the pocket in which catalysis occurs
- 6. the reactant on which an enzyme works
- 7. a macromolecule serving as a catalyst, a chemical agent that increases the rate of a reaction without being consumed by the reaction. most enzymes are proteins
- 9. a chemical agent that selectively increases the rate of a reaction without being consumed by the reaction