Across
- 1. Pyruvate dehydrogenase in _______ when it becomes phosphorylated
- 8. The second reaction in the citric acid cycle is an example of this type of chemical transformation
- 11. This is the number NADH that are produced during one full turn of the citric acid cycle
- 12. This molecule is a co-substrate of the pyruvate dehydrogenase complex (use as one word)
- 13. This molecule is the substrate of fumarase enzyme in the citric acid cycle
- 14. This enzyme produces FADH2 in the citric acid cycle and also as Complex II in the electron transport chain
- 17. This molecule is produced from L-malate catalyzed by malate dehydrogenase
- 19. This enzyme in the citric acid cycle is controlled by citrate levels (use abbreviation)
- 20. Isocitrate dehydrogenase releases this molecule from isocitrate
Down
- 2. This electron carrier is produced during the last oxidative decarboxylation in the citric acid cycle catalyzed by alpha-ketoglutarate dehydrogenase complex
- 3. This enzyme catalyzes the condensation of acetyl-CoA and oxaloacetate
- 4. This thioester is produced by the alpha-ketoglutarate dehydrogenase complex (use as one word)
- 5. This prosthetic group, cofactor is regenerated while producing NADH in the final steps pyruvate dehydrogenase complex
- 6. This ring system can be produced from Succinyl-CoA, the iron coordinating ring systems found in the cytochromes in the electron transport chain
- 7. This molecule in the citric acid cycle is an intermediate in the biosynthesis of fatty acids and sterols
- 9. This enzyme catalyzes the oxidative decarboxylation of pyruvate (use abbreviation)
- 10. This enzyme produces GTP via substrate-level phosphorylation in the citric acid cycle; Succinyl-CoA __________
- 15. This atom is a positive allosteric activator of several enzymes in the citric acid cycle
- 16. NADH and Acetyl-CoA can inhibit pyruvate dehydrogenase which is an example of this type of inhibition mechanism
- 18. This molecule is an inhibitor and negative allosteric regulator of the citric acid cycle