Across
- 2. ball of cells produced by cleavage
- 4. acronym for mitosis-promoting-factor, major factor in regulation of early blastomere cell cycles
- 7. eggs with only a small area of the egg that is free of yolk (eg: bird and fish eggs)
- 10. splitting of a single cellular sheet into two parallel sheets – results in a second new epithelial sheet of cells (eg: mammal hypoblast formation)
- 12. __________ cleavage: complete/total cleavage, includes isolecithal and mesolecithal cleavage
- 14. larger subunit of mitosis-promoting-factor, regulates the smaller subunit and controls MPF
- 17. migration of the embryo’s surface cells to the interior (individual cells are able to move independently from one another)
- 18. pole high in yolk concentration
- 19. __________ cleavage: when cell divisions only happen in a small disc of cytoplasm free of yolk
- 20. acronym for mid-blastula transition, changes include 1) introduction of gap stages G1 and G2 2) cell division synchronicity is lost – cells “go their own way” 3) new mRNAs are transcribed from zygotic genome
- 21. inward movement of an expanding outer layer, the cells of this layer spread over the internal surface of the remaining external cells (eg: amphibian mesoderm)
- 22. eggs with a yolk in the center (eg: insect eggs)
Down
- 1. eggs with sparse and equally distributed yolk
- 3. when epithelial sheets move as a unit (not individually) and enclose the deeper layers of an embryo (multiple mechanisms, including cell division, cells changing shape, or layers of cells radially moving)
- 5. pole low in yolk concentration
- 6. __________ cleavage: incomplete cleavage, includes telolecithal and centrolecithal cleavage
- 8. _________ furrow: the indentation that expands and ultimately splits the cell
- 9. process through which the “body plan” of the organism is established from the three germ layers (endoderm, mesoderm, and ectoderm)
- 11. amount and distribution determines where cleavage can occur and the relative size of blastomeres
- 13. localized infolding of a sheet of cells (epithelium) without cells losing their tight adhesive connections
- 14. acronym for cyclin-dependent kinase, smaller subunit of MPF that regulates mitosis through phosphorylation
- 15. ____________ extension: when lateral cells from all germ layers move towards the midline, leading to convergence of these cells. A way for the embryo to grow and extend along its axis.
- 16. _________ cleavage: occurs around the periphery of a cell, divisions only happening in the rim of the cytoplasm
