Clinical Hematology: "Crosswords"

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Across
  1. 1. X-linked bleeding disorder caused by a deficiency of a clotting factor.
  2. 6. Gradual, slow (weeks to months or years).
  3. 7. Increase in the most common type of white blood cell, often seen in bacterial infection.
  4. 10. Descriptive term for a red blood cell larger than normal (high MCV).
  5. 11. Primary protein used to store iron inside the cells.
  6. 12. Condition caused by impaired DNA synthesis.
  7. 16. Large bone marrow cell that produces platelets.
  8. 21. A general process of red blood cell destruction.
  9. 23. General term for variation in the shape of red blood cells.
  10. 24. Term for lethal or deadly.
  11. 25. Rare condition of an elevated absolute count of basophils.
  12. 27. The red, oxygen-carrying protein found in red blood cells.
  13. 29. Malignant tumor or neoplasm.
  14. 30. An increase in the concentration of red blood cells.
  15. 32. studies Laboratory panel measuring serum iron, total iron-binding capacity (TIBC), and ferritin.
  16. 33. Decrease in the number of eosinophils in the peripheral blood.
  17. 35. A low count of monocytes.
  18. 41. Anemia caused by the premature destruction of red blood cells.
  19. 48. A key element needed to build hemoglobin, deficient in a common anemia type.
  20. 49. Green-colored tumor of myeloblasts, an extramedullary manifestation of AML.
  21. 52. A monocyte that has engulfed the nucleus of another cell.
  22. 53. An older term for a dense, contracted red blood cell.
  23. 55. Red fluid in veins and arteries.
  24. 56. Condition indicated by the presence of ringedsideroblasts in the bone marrow.
  25. 60. Also known as a thrombocyte.
  26. 67. Descriptive term for a platelet adherent to a red blood cell.
  27. 70. Spoon-shaped nails, a classic physical sign of chronic iron deficiency.
  28. 71. Cancer that originates in the lymph nodes or lymphatic tissue.
  29. 72. Rare extramedullary tumor composed of immature myeloid cells.
  30. 74. Myeloproliferative neoplasm characterized by bone marrow scarring.
  31. 75. Increase in the white blood cell count often associated with parasitic infection or allergy.
  32. 76. Remnant of a ruptured white blood cell.
  33. 77. A term for a red blood cell that is normal in size.
  34. 78. Destruction of red blood cells by the body's own antibodies.
  35. 79. Common oral medication used to treat iron deficiency anemia.
  36. 80. Slowly progressing blood cancer that may be observed for a period before treatment is needed.
Down
  1. 2. Nucleated precursor cell of an erythrocyte found in the bone marrow.
  2. 3. Condition characterized by a deficiency in red blood cells or hemoglobin, leading to fatigue.
  3. 4. Low absolute count of the most numerous white blood cells.
  4. 5. cell Erythrocyte that resembles a bull's-eye when stained.
  5. 8. Most common childhood blood cancer.
  6. 9. The non-protein part of hemoglobin.
  7. 13. Severe, potentially life-threatening drop in granulocyte count.
  8. 14. Cancer of plasma cells, often resulting in lytic bone lesions.
  9. 15. Macrocytic anemia resulting from a lack of intrinsic factor (B12 malabsorption).
  10. 17. A form of Acute Myeloid Leukemia (AML) involving a significant component of the red blood cell line (FAB M6).
  11. 18. Reduction in the total number of white blood cells.
  12. 19. Abnormal hemoglobin resulting from a fusion of delta and beta chains.
  13. 20. Bone marrow failure resulting in a deficiency of all three blood cell lines.
  14. 22. Genetic disorder causing red blood cells to be spherical and fragile.
  15. 26. Chemical stain used to demonstrate the presence of iron in cells.
  16. 28. An increase in the large phagocytic white blood cells (monocytes).
  17. 31. Rare chronic leukemia characterized by lymphocytes with fine cytoplasmic projections.
  18. 34. Acquired clonal stem cell disorder resulting in red cell lysis.
  19. 36. Fragmented red blood cell, often a sign of MAHA.
  20. 37. Term for variation in red blood cell size.
  21. 38. Condition where red blood cells are fragmented by passing through damaged small blood vessels (MAHA).
  22. 39. A characteristic cerebriform T-lymphocyte.
  23. 40. Aggregates of ribosomes seen as small blue granules in red blood cells.
  24. 42. Descriptive term for a red blood cell smaller than normal (low MCV).
  25. 43. Sudden, rapid (hours to days).
  26. 44. More specific term for red cell destruction caused by the body's own antibodies.
  27. 45. Adjective for a lack of color, common symptom of low Hb.
  28. 46. Technical term for any white blood cell.
  29. 47. An atypical lymphocyte, classically associated with infectious mononucleosis.
  30. 50. Reduction in the counts of all three blood cell types.
  31. 51. cell A terminally differentiated B-lymphocyte that secretes antibodies.
  32. 54. A group of disorders caused by defects in the heme synthesis pathway.
  33. 57. Most common cause of microcytic anemia worldwide.
  34. 58. Rapidly progressing blood cancer requiring immediate, aggressive treatment.
  35. 59. Lower than normal count of basophils.
  36. 61. syndrome Rare, inherited anemia often associated with physical abnormalities and bone marrow failure.
  37. 62. Increase in the white blood cells crucial for adaptive immunity, common in viral infections.
  38. 63. A low count of the cells responsible for clotting.
  39. 64. Inherited red blood cell disorder that causes cells to assume a crescent.
  40. 65. Immature, non-nucleated red blood cells, indicating recent bone marrow output.
  41. 66. Abnormally high total white blood cell count.
  42. 68. White blood cell type characterized by the presence of granules in its cytoplasm
  43. 69. An abnormally high platelet count.
  44. 73. Cancer of the blood-forming tissues.