CNS Depression Crossword

3. A collection of brain regions affected by depression.
4. A dietary amino acid associated with MAO-I induced hypertensive crisis.
5. The acronym for Selective Serotonin Reuptake Inhibitor.
6. This is the only parenteral antidepressant.
10. A deficit in neuronal growth caused by reduced BDNF.
11. CYP2D6 exhibits.
12. A medical condition frequently associated with MDD.
13. Carries an indication for smoking cessation (brand).
15. SSRIs, SNRI, mirtazapine and this agent are 1st line agents for mild-moderate MDD.
17. Tertiary TCAs undergo _____ to form secondary TCAs.
18. Have a higher reported incidence of MDD.
19. ___________ doses are higher for depression treatment than insomnia.
20. _________ is rated a category X antidepressant medication in pregnancy.

1. Effects that contribute to poor PO bioavailability of certain antidepressants.
2. This occurs due to overstimulation of neurotransmitter autoreceptors and delays therapeutic response to antidepressants.
7. Dopamine is an example of a ______.
8. The adverse effect caused by antagonism at a-1 adrenoreceptors.
9. A process to monoamine function that is inhibited by phenelzine.
14. If switching to an MAOI from ______, a patient must wait a 5-6 week washout period.
16. ________ is a catecholamine with reduced expression in depressed patients.