Components of Blood and RBCs

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Across
  1. 8. What is stored in the axial skeleton, ribs, pelvis, as well as the long bones of infants
  2. 10. Globular protein with 2 alpha and 2 beta chains that can bind 4 oxygen molecules
  3. 11. The hormone that tells bone marrow to produce more RBCs, affected by: altitude, blood donation, kidney failure, and renal stenosis
  4. 12. Accumulation of bilirubin that would normally be excreted by the liver
  5. 13. Liquid extracellular matrix that makes up 55% of total blood and is composed of water, hormones, proteins, glucose, etc
  6. 14. The component of blood that makes up 1% of the total volume and is composed of white blood cells and platelets
  7. 15. Makes up 45% of total blood volume and is composed of RBCs and hematocrit
Down
  1. 1. Biconcave discs with strong, flexible membrane, no nucleus, and no mitochondria, full of hemoglobin
  2. 2. The fraction of blood that, following centrifugation, is composed of mainly WBCs and platelets
  3. 3. The oxygen state of the blood that is sensed by the kidneys, leading to RBC production
  4. 4. Iron center of hemoglobin
  5. 5. Its globular protein is broken down into amino acids
  6. 6. The process by which formed elements of the blood develop
  7. 7. Disease state that can be caused by lack of RBC production, early RBC death, or rate of RBC destruction exceeding rate of production
  8. 9. The lifespan of an RBC in circulation (hint: # of days spelled out)