Across
- 4. Convict antagonist in The Sign of Four
- 5. London blackmailer and Doyle’s possible inspiration from real life
- 8. Real-life American criminal said to have inspired Doyle’s Moriarty
- 11. Female conspirator and murderer in The Disappearance of Lady Frances Carfax
- 13. Villain portrayed by Jared Harris in A Game of Shadows
- 14. Collector of “The Red Circle” and shadowy criminal figure
- 17. Sadistic assassin who serves Moriarty in The Final Problem
- 20. Holmes’ nemesis’ brother, also a professor
- 21. Holmes opponent in The Valley of Fear and Moriarty’s lieutenant
- 22. Modern U.S. adaptation’s villainess, Irene Adler’s alter ego
- 23. Downey film villain obsessed with black magic and politics
- 25. Ruthless blackmailer from The Adventure of Charles Augustus Milverton
Down
- 1. Swindler who posed as a suitor in The Solitary Cyclist
- 2. Mysterious killer and escaped convict in The Boscombe Valley Mystery
- 3. Fiend behind the Baskerville family curse
- 6. Snake-wielding killer from The Speckled Band
- 7. Holmes’ arch-nemesis, “the Napoleon of Crime”
- 9. Fictionalized Holmes foe inspired by Jack the Ripper in many adaptations
- 10. Modern BBC villain who fakes his death at St. Bart’s
- 12. Villainous governess in The Copper Beeches
- 15. Fiendish rival who kills Bartholomew Sholto
- 16. Disguised impostor in A Case of Identity
- 18. Holmes villain with a false arm in The Engineer’s Thumb
- 19. Woman who outsmarts Holmes in “A Scandal in Bohemia” — though not evil
- 24. Murderous nobleman in The Abbey Grange