CROSSWORD

2. Antiretroviral boosted intentionally by CYP3A4 inhibition
8. The 'Grey Baby Syndrome' is a well-known ADR associated with which antibiotic in neonates due to their immature glucuronidation capacity
10. H2 blocker withdrawn over NDMA impurity
12. Toxic excipient contaminant linked to fatal paediatric cough syrup outbreaks
14. Specific form to compile a spontaneous report of drug toxicity in the United Kingdom
15. Assessment of drug event relationship

1. In 2004 this NSAID was shown to increase risk of heart attack and stroke leading to its withdrawal from the market
3. A drug that causes fetal abnormalities when administered to a pregnant woman
4. This drug is notorious for causing 'Red Man Syndrome', a pseudoallergic reaction, if infused too rapidly
5. Congenital limb defect classically linked to thalidomide
6. A genetically determined abnormal reactivity to a drug is best described as
7. Information suggesting a possible drug event link
9. Standardized medical terminology for safety reporting
11. Drug contraindicated with nitrates due to profound hypotension
13. Name of the MDAE reporting system used in the European Union Online