Crossword puzzle

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Across
  1. 2. – Tiny needles that create microchannels for drug delivery.
  2. 5. – Drug property that enhances skin permeability.
  3. 7. – Use of ultrasound waves to improve percutaneous absorption.
  4. 9. – Ability of patch to stick properly to the skin surface.
  5. 10. – TDDS design with drug in a liquid or gel compartment separated by a membrane.
  6. 12. size – Small drugs (≤500 Da) are more likely to cross the skin.
  7. 13. – TDDS design where drug is dispersed in a polymer layer.
  8. 14. applications – Common uses like pain control, hormone therapy, smoking cessation.
Down
  1. 1. – Movement of drug molecules through skin layers.
  2. 3. – Substance that increases drug penetration through the skin.
  3. 4. – Patient education to ensure proper use of TDDS.
  4. 6. – Technique using electric current to enhance drug absorption.
  5. 8. – Adhesive system applied to skin for controlled drug release.
  6. 11. corneum – The outermost skin layer and main barrier to drug absorption.
  7. 14. release – Continuous drug delivery over a prolonged period.