Across
- 1. The median age of diagnosis of Cystic Fibrosis is 6 to 8 _______
- 4. _______ is the preferred treatment for individuals with CFRD
- 5. Patients with CFRD may have falsely ___ hemoglobin A1c levels
- 6. Pulmonary ________ testing is used for evaluating and monitoring the progression of Cystic Fibrosis
- 7. Patients with Cystic Fibrosis should be ____________ at the sign of acute illness
- 12. The most common pulmonary function test is _________
- 13. ______________ complications are the most common complications in patients with CFRD
- 16. Patients with Cystic Fibrosis have thicker _____ secretions on epithelial linings
- 17. Gallbladder disease is common in patients with Cystic Fibrosis, with up to 15% having __________
- 20. The mutation that causes Cystic Fibrosis leads to premature destruction of the _____ apparatus
- 21. Mucus plugging in the ___________ results in obstructive lung disease
- 22. Cystic Fibrosis-related diabetes is believed to be ______________
- 23. ____________ is common in Type I Diabetes but not in CFRD
- 26. Patients with Cystic Fibrosis live to about the ______ decade of life before needing a lung transplant
- 28. The mutation that causes Cystic Fibrosis is found on Chromosome _____
- 31. Patients with CFRD may develop insulin ___________ leading to increased insulin requirements
- 32. _________ was the first CFTR modulator to become available for use in the United States
- 35. An increased risk factor for CFRD is premature loss of ________ function
- 36. Obstruction caused by mucus plugging creates an optimal environment for _________ growth
- 37. ____ modulator therapies are designed to correct dysfunction
- 38. Females with Cystic Fibrosis may be infertile due to thickened ________ mucus
- 39. Males with Cystic Fibrosis may be infertile due to ______ vas deferens
- 41. A pulmonary ____________ is the worsening of lung function due to infection
- 42. Pancreatic malfunction in patients with Cystic Fibrosis leads to Type I ________
- 44. Cystic Fibrosis is a _______ disease
- 45. Cystic Fibrosis is the most _____ genetic disorder among Caucasians
- 46. Cystic Fibrosis is caused by a ________
Down
- 2. _____ disease occurs in patients with Cystic Fibrosis because of an increase in secretion viscosity
- 3. The most common cause of death in Cystic Fibrosis patients is end-stage ____ disease
- 5. Lung transplantation does not cure Cystic Fibrosis, only offers a relief of symptoms and prolongs ____
- 8. A medication for Cystic Fibrosis patients that became available for use but only in combination with ivacaftor for patients who are homozygous for the Phe508del mutation is __________
- 9. Monitoring growth and ______ trends is crucial in pediatric patients with CFRD
- 10. __________ are vital for patients with CFRD for education and insulin management
- 11. The result of mutations is an increased resorption of ______
- 14. Patients with Cystic Fibrosis have high levels of ____ in their sweat
- 15. Cystic Fibrosis management involves clearing mucus in airways and controlling ___________ infection
- 18. Pancreatic manifestations in Cystic fibrosis patients are due to obstruction of pancreatic ________
- 19. Adult patients with Cystic Fibrosis are most likely to be _________
- 22. Intestinal involvement is most likely seen when the patient is born with ________ ileus
- 24. The result of mutations is a decreased secretion of ________
- 25. CFTR mutations result in abnormal beta-cell function with _________ insulin secretion
- 27. A defective CFTR protein causes structural damage to pancreatic _____ cells
- 28. Newborns are screened for Cystic Fibrosis as part of a ________ newborn screening panel
- 29. During trials for ivacaftor, there was a large occurrence of patients with increased serum ________________ levels
- 30. The third medication for Cystic Fibrosis patients to become available was __________
- 33. Cystic Fibrosis has no ____
- 34. he two primary goals for managing pulmonary illness are to treat the infection and improve ___________
- 40. Cystic Fibrosis patients have ______ lungs in utero, at birth, and after birth
- 43. The treatment for end-stage lung disease is lung ___________
- 45. Patients with Cystic Fibrosis are encouraged to consume a high ___ diet
