Cytokines

Edit Answers
12345678910111213141516171819202122232425262728293031323334
Across
  1. 1. Stimulates T cell activation
  2. 4. IFN-lambda; secreted by dendritic cells
  3. 7. Pro-survival for B cells
  4. 8. "signal___"
  5. 10. Class I; IL-6, IL-12, IL-23
  6. 13. Test on multi-well plate; flourescent intensity indicates amount of target substance
  7. 14. Hormones; type of cytokine action
  8. 18. mAb; disrupts cytokine-driven inflammatory response
  9. 20. Th2, worm infection, B cells makes IgE
  10. 21. "pro-__"; IL-17 function
  11. 23. IL-1 function
  12. 30. one cytokine inactivates the other
  13. 31. Can describe most cytokines; opposite of insoluble
  14. 32. Cytokine; directs leukocyte migration
  15. 34. Cytokine action; binds to oneself
Down
  1. 2. A rapid point of care tests, uses mAbs
  2. 3. Cytokines released to nearby cells
  3. 5. movement of blood cells out of capillaries, into tissue
  4. 6. Type of interferon-- adaptive, dimeric
  5. 9. >=2 cytokines induce greater effect
  6. 11. Uses hybridomas, treatments also end in these letters
  7. 12. Cell death/survival; proinflammatory
  8. 15. Type of interferon-- innate, dimeric
  9. 16. artificially manufactured antibody
  10. 17. NK; membrane bound TNF
  11. 19. pro-inflammatory; innate; pyrogen
  12. 22. Many cytokines have same effect
  13. 23. One cytokine produces multiple effects
  14. 24. Amino acid used by chemokines
  15. 25. Antiviral class; increases MHC
  16. 26. IL-2, 4, 6, 12, 23
  17. 27. Antibody induction method, high variety and natural
  18. 28. Virus that uses CCR5; CD4+ for cell entry
  19. 29. excessive, uncontrolled cytokine release
  20. 33. With B cells, used to make hybridoma