Cytoskeleton, ECM, and Motors

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Across
  1. 1. highly anionic molecules in the ECM
  2. 4. the thick filament has myosin heads that face in opposite directions, hence being termed this
  3. 9. a disease often characterized by people having long skinny fingers and often very tall and thin in stature (Osama bin Laden was thought to have this disease)
  4. 10. this molecule with a sulfate group can be taken to help keep joints supple
  5. 11. this molecule of the ECM has high tensile strength and is often injected into people's lips
  6. 12. for all three cytoskeletal filament, you need more than one of these to generate the complete filament
  7. 16. a tyrosine kinase that acts at a checkpoint for B cells
  8. 19. this special amino acid has an imino group instead of an amino group at its N-terminus
  9. 21. the structure found within a skeletal muscle fibril and which contains actin and the thick filament
  10. 22. a deficiency of Vitamin C results in this disease
  11. 23. the state that a kinesin motor is in when it is ATP-bound
Down
  1. 2. tubulin binds to this nucleotide
  2. 3. the place in the cell where lysosomes reside when a molecule such as RILP is overexpressed
  3. 5. the actin that is found on the edge of cells
  4. 6. negative end motor for microtubules
  5. 7. this molecule covers the elastic extracellular matrix molecule elastin helping to keep it from stretching too far
  6. 8. actin and microtubules can elongate and shrink very quickly and are said to be this
  7. 13. a sequence of amino acids found in integrins important for binding fibronectin
  8. 14. a disease associated with neurofilaments
  9. 15. subunit of the microtubules, both alpha and beta
  10. 17. the repeating sequence found in collagen fibers
  11. 18. this molecule wraps around actin and prevents myosin thick filament heads from binding in the absence of calcium
  12. 20. the name of the British sailors after the discovery of what was lacking in people that had scurvy