Developmental and Cancer Genetics

12345678910111213141516171819
Across
  1. 4. Programmed cell death, either during development or as “cellular suicide” for diseased cells
  2. 10. These genes encode proteins with functions necessary for cellular upkeep, metabolism and protein synthesis
  3. 11. Signal _______ is the general word for how an extracellular signal is passed through the cell membrane to effect things inside the cell
  4. 12. This technology uses small DNA probes to study the gene expression of many genes simultaneously by assaying all mRNA expressed in a tissue.
  5. 13. In ________ division, the two daughter cells of mitosis and cytokinesis are nonidentical and can have different cell fates
  6. 14. This is the process in which cells begin to express different sets of genes and ultimately become different tissue types.
  7. 17. This type of gene is dominant when mutated and can produce a cancer
  8. 19. In ______ mutants, the identity of one body structure has been changed into another.
Down
  1. 1. This type of mutation makes cells more likely to accumulate genetic errors.
  2. 2. This interesting property of Hox genes means that their expression order along the body of an animal is the same order they are found in on the chromosome.
  3. 3. When a cell’s fate is determined by a message it receives from another cell, cell to cell ______ has occurred
  4. 5. A cell that is going to divide must pass through several of these potential stopping points throughout the cell cycle
  5. 6. Tumor ________ genes are genes which are recessive when mutated, but can produce a cancer
  6. 7. This type of mutation affects more than one phenotype
  7. 8. This type of gene makes a product that is deposited into an egg by the female
  8. 9. Cells acquire different tissue identities and fates by expressing different ____ factors
  9. 15. This type of mutation is passed on to one’s offspring
  10. 16. This is a highly conserved stretch of DNA sequence present in Hox protein coding sequences
  11. 18. A _______ mutation makes the phenotype of another mutation more dramatic