Across
- 1. Dandy-walker malformation is an absence of the cerebellar ___, and is characterized by an enlarged posterior fossa
- 3. Sturge-weber syndrome consists of a capillary hemangioma in the distribution of cranial nerve V1/V2(___ stain), angiomas(blood vessel tumor) in the leptomeninges that are associated with calcifications, hemiparesis, and intellectual disability. Associated mutation is GNAQ
- 6. ___ is when too much unconjugated bilirubin in an infant causes cns damage and a yellow stained brain.
- 7. One of the most gruesome neural tube defects is ___, which is an absence of most of the brain and skull. Findings include polyhydramnios and increased afp(not in Dr. Vogel’s lecture but good for boards)
- 8. ___ is a protrusion of brain through a part of the skull, like the occiput or through the nose.
- 9. ___ deficiency increases the risk of neural tube defects, so it makes sense that ___ antagonists are teratogens.
- 10. Germinal matrix hemorrhage in infants can cause bleeding into the ventricles can be associated with respiratory distress and impaired cognition. ___ is a main risk factor.
Down
- 2. Holoprosenchephaly is a defect characterized by incomplete separation of the cerebral hemispheres. One of the more severe outcomes is “cyclopia”. It is associated with ___ mutations.
- 4. ___ is the absence of gyri of the brain, which may cause a smooth-surfaced brain. In contrast, polymicrogyria is when you have many small irregular gyri.
- 5. ___ is a herniation of cns tissue(spinal cord) and meninges through the vertebrae, while meningocele is just a herniation of the meninges.