Across
- 1. German physician and physiologist who demonstrated the pancreatic origin of diabetes through pancreatectomy experiments in dogs.
- 3. Rare neurodegenerative disorder characterized by juvenile-onset diabetes mellitus, optic atrophy, deafness and diabetes insipidus.
- 4. Canadian physician awarded the 1923 Nobel Prize in Physiology or Medicine for the discovery of insulin.
- 6. Rebound hyperglycemia following nocturnal hypoglycemia, classically associated with excessive insulin administration.
- 9. Dual GIP and GLP-1 receptor agonist approved for the treatment of type 2 diabetes mellitus and obesity.
Down
- 2. German physician whose surname is associated with nodular glomerulosclerosis in diabetic nephropathy.
- 5. Gut-derived hormones that enhance glucose-dependent insulin secretion following nutrient ingestion.
- 7. Glucose transporter responsible for insulin-independent glucose uptake by pancreatic β-cells and hepatocytes.
- 8. Potassium channel opener used in the management of insulinoma-associated hypoglycemia.
- 10. Technosphere-based inhaled human insulin formulation approved for prandial glycemic control.