Diseases caused by Prions Viroids and Virusoids

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Across
  1. 3. It is caused by prions, historically linked to ritualistic cannibalism.
  2. 7. ________Jakob Disease (CJD): Caused by misfolded prion proteins (PrPSc).
  3. 8. _________Cadang-Cadang Disease: Caused by Coconut Cadang-Cadang Viroid (CCCVd).
  4. 9. ________Tobacco Mottle Disease: Caused by a virusoid associated with Tobacco Necrosis Virus.
Down
  1. 1. ___________ Spongiform Encephalopathy (BSE): Caused by prions, also known as "Mad Cow Disease."
  2. 2. _________Transient Streak Disease: Caused by a virusoid associated with Lucerne Transient Streak Virus.
  3. 4. ________Spindle Tuber Disease: Caused by Potato Spindle Tuber Viroid (PSTVd).
  4. 5. _________Familial Insomnia (FFI): Caused by a mutation in the prion protein gene (PRNP).
  5. 6. It is Caused by Hepatitis D Virus (HDV), requiring Hepatitis B Virus as a helper.
  6. 8. ________Exocortis Disease: Caused by Citrus Exocortis Viroid (CEVd).