Drug Discovery & Development

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Across
  1. 2. is the final phase of drug discovery that focuses on optimizing different characteristics of lead compounds, such as target selectivity, biological activity, potency, and toxicity potential
  2. 4. used to make a prescription drug called digoxin.patent is a legal document granting an inventor exclusive rights to their invention, preventing others from making, using, or selling it without permission.
  3. 5. is the study of the complete set of genes (the genome) of organisms, of the way genes work, interact with each other and with the environment
  4. 8. compound is confirmed as positive when an assay is repeated
  5. 9. the process of finding a biological target such as a protein or nucleic acid element with an activity that a therapeutic can regulate.
Down
  1. 1. the study of the interactions, function, composition, and structures of proteins and their cellular activities
  2. 3. decision to focus on finding an agent with a particular biological action that is anticipated to have therapeutic utilityPROTEOMICS
  3. 6. treatment for malaria infection for over 300 years.
  4. 7. compound giving positive results in a screening assay