ec puzzle num 2

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Across
  1. 5. enzymes whose continual activity is required at the DNA replication fork.
  2. 6. The lagging strand is a single DNA strand that, during DNA replication, is replicated in the 5' - 3' direction (opposite direction to the replication fork).
  3. 9. a group of two or more associated polypeptide chains.
  4. 10. binds with high affinity in a cooperative manner to single-stranded DNA
Down
  1. 1. enzymes that create DNA molecules by assembling nucleotides, the building blocks of DNA.
  2. 2. short sequences of DNA nucleotides
  3. 3. a structure that forms within the long helical DNA during DNA replication.
  4. 4. a single DNA strand that, during DNA replication, is replicated in the 3' – 5' direction (same direction as the replication fork).
  5. 7. An enzyme that closes nicks or discontinuities in one strand of double-stranded DNA by creating an ester bond between adjacent 3' OH and 5' PO4 ends on the same strand.
  6. 8. enzymes that bind and may even remodel nucleic acid or nucleic acid protein complexes