Effector functions

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  1. 3. In a viral infection, T helper cells are most likely to differentiate into the Th-__ subset (spell the number).
  2. 7. Signature cytokines produced by Th17 cells are IL-22 and IL-___ (spell the number).
  3. 8. IgA is said to be responsible for what type of immunity?
  4. 9. What shape are IgM molecules secreted in?
  5. 12. Which isotype is used to opsonise parasites, but is also involved in allergic disease?
  6. 13. Cytotoxic (killer) T cells can engage a receptor on infected cells to trigger the cell’s apoptosis. What is this receptor called?
  7. 16. In a fungal infection, the cytokine produced by Th cells recruits an innate immune cell that can phagocytose and kill this pathogen. What are these innate immune cells?
  8. 18. Mycobacterium tuberculosis is a bacterium that multiplies inside host cells. The T helper subset most suited to its elimination is Th-___ (spell the number).
  9. 19. Th1-produced cytokines are known to activate what type of innate immune cell?
  10. 20. B cells that can make either IgG, IgA or IgE are said to have done what
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  1. 1. When cytotoxic (killer) T cells kill a cell using cytotoxic enzymes they first create pores in this target cell. What is the name of the molecule that allows them to do this?
  2. 2. The name of the Th subset that ‘helps’ B cells to undergo antibody isotype switching is T-______ helper cells.
  3. 4. In a parasitic infection, helper T cell cytokine production should activate an innate immune cell that can kill the parasite. What are these innate immune cells?
  4. 5. The Th subset most suited to fighting a fungal infection is Th-___ (spell the number).
  5. 6. A signature cytokine produced by Th1 cells is Interferon-_______.
  6. 10. Three signature cytokines produced by Th2 cells are IL-4, IL-5 and IL-___ (spell the number).
  7. 11. Cytotoxic (killer) T cells can kill an infected cell using enzymes stored in their cytotoxic granules. What are these enzymes called?
  8. 14. About 20% of Australians are affected by a maladaptation of the Th2 response, which results in ______ disease.
  9. 15. A parasitic infection needs a Th-___ subset response (spell the number).
  10. 17. Which antibody isotype is the most abundant in blood and has the most effector functions?