Endo

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Across
  1. 5. Deep, labored, rapid breathing seen in metabolic acidosis, especially diabetic ketoacidosis (DKA), as the body tries to blow off CO₂.
  2. 9. A condition caused by prolonged exposure to high cortisol levels. Signs include moon face, buffalo hump, truncal obesity, purple striae, and muscle weakness.
  3. 10. Destruction or removal of tissue, often used to treat hyperfunctioning endocrine glands (e.g., radioactive iodine ablation for hyperthyroidism).
  4. 11. A disorder caused by excess growth hormone in adults, leading to enlarged hands, feet, and facial features. Usually due to a pituitary adenoma.
  5. 14. Rapid or extreme fluctuations in emotion or physiological state. Can be seen in endocrine disorders affecting mood, like hyperthyroidism or Cushing’s syndrome.
  6. 15. Originating from within the body. For example, endogenous insulin is produced by the pancreas.
  7. 16. A byproduct of fat metabolism, often elevated in uncontrolled diabetes or starvation. Presence of ketones in urine or blood may indicate ketoacidosis.
  8. 17. Tissue or organ that a hormone specifically affects due to the presence of compatible receptors.
  9. 19. A type of corticosteroid (e.g., aldosterone) that helps regulate sodium and potassium balance, and fluid volume.
  10. 20. Increased or excessive urine production. Can be caused by diuretics, hyperglycemia, or endocrine disorders like diabetes insipidus.
Down
  1. 1. Another term for thyroid storm—a severe form of hyperthyroidism requiring urgent treatment.
  2. 2. Excess growth hormone secretion in children or adolescents before epiphyseal plate closure, leading to abnormally large stature.
  3. 3. Originating from outside the body. For example, exogenous insulin is administered to treat diabetes mellitus.
  4. 4. Hormones made by the adrenal medulla (e.g., epinephrine and norepinephrine) involved in the “fight or flight” response.
  5. 6. Protrusion of the eyeballs, commonly seen in Graves’ disease (a form of hyperthyroidism).
  6. 7. Cells that have specific receptors for hormones, allowing them to respond to particular endocrine signals.
  7. 8. A rare, life-threatening condition of extreme hyperthyroidism. Symptoms include fever, tachycardia, hypertension, and delirium. Requires emergency care.
  8. 12. A life-threatening emergency caused by acute adrenal insufficiency. It presents with hypotension, hyponatremia, hyperkalemia, hypoglycemia, and shock. Requires immediate glucocorticoid replacement.
  9. 13. A class of corticosteroids (e.g., cortisol, prednisone) that affect metabolism and immune response. Used to treat inflammation, adrenal insufficiency, and autoimmune disorders.
  10. 18. A state where thyroid function is normal, with balanced levels of thyroid hormones (T3, T4, and TSH).