Enzyme

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Across
  1. 2. absorbs free energy from the surroundings
  2. 5. sum of all the chemical reactions occurring in the cell
  3. 8. energy required to start a chemical reaction
  4. 10. flexible active site that changes shape to conform to the substrate
  5. 11. breaking down large molecules into smaller ones
  6. 12. substrate molecules fit perfectly into active site
Down
  1. 1. making large molecules from smaller ones
  2. 3. net release of free energy
  3. 4. have more stored energy than the products of the reaction.
  4. 6. an organic cofactor
  5. 7. have more stored energy than the reactants of the reaction
  6. 9. molecules that inhibit the activity of enzymes, reducing the reaction rate.