Enzyme crossword

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Across
  1. 2. Substrates in a chemical reaction
  2. 3. Make small molecules from large ones
  3. 6. Reaction that absorbs free energy from surroundings
  4. 7. Model that describes an active site with a complementary shape (use _ as spaces)
  5. 10. Make large molecules from small ones
  6. 12. Biological catalyst
  7. 13. Minimum amount of energy needed to start a chemical reaction (use _ as spaces)
Down
  1. 1. Reaction that releases free energy into the surroundings
  2. 4. Molecules that reduce or stop an enzyme from functioning
  3. 5. Sum of all chemical reactions in a cell/organism
  4. 8. Model that describes an active site that changes shape when a substrate approaches (use _ as spaces)
  5. 9. Organic molecules that help enzymes in functioning
  6. 11. Substances created after chemical reaction