Enzymes vocab crossword puzzle

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Across
  1. 5. Energy needed to start a reaction
  2. 6. Reaction that absorbs heat energy
  3. 7. Starting substances in a chemical reaction
  4. 9. Reaction that releases heat energy
  5. 11. Enzyme loses shape and cannot function
Down
  1. 1. Region on enzyme where substrate binds
  2. 2. Substance that speeds up a reaction
  3. 3. Substances formed during a reaction
  4. 4. Process of atoms being reorganized
  5. 8. Proteins that act as biological catalysts
  6. 10. Reactants that enzymes act upon