Across
- 3. dissociation constant for enzyme substrate complex
- 10. has high affinity for an active site
- 11. interaction not involved in substrate binding
- 12. mode of substrate binding
- 13. where competitive inhibitor binds
- 15. required for some reactions
- 16. complete catalytic species
Down
- 1. may be diffusion-controlled
- 2. unlikely catalytic residue
- 4. polarizes water
- 5. general acid or base
- 6. covalent intermediate with a Lys residue
- 7. maximal rate for an enzyme
- 8. inhibitor that reduces turnover number
- 9. specificity for functional group shapes
- 14. inhibitor of ATCase