Exam 2 Immunology

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Across
  1. 2. ___ T cells prevent the immune system overreaction
  2. 5. ___ immunity uses B cells and T cells
  3. 7. Second signal required for B and T cell activation
  4. 9. Selection process favoring cells that can recognize and bind to self-antigens and MHC molecules
  5. 12. Co-receptor on killer T cells that bind to class I MHC molecules
  6. 13. When a T cell has recognized its cognate antigen, but not the second signal for activation
  7. 14. Th_ Th cells have not committed to a cytokine profile
  8. 16. Selection process killing cells that bind too strongly to self-antigens
  9. 18. Th_ Th cells release IL-17 and IL-21
  10. 21. ___ immunity provides a quick response
  11. 24. Co-receptor on Th cells that bind to class II MHC molecules
  12. 26. B cells mature in ___
  13. 27. ___ T cells identify and destroy tumor cells and virus-infected cells
Down
  1. 1. Epithelial cells in the ___ produce cytokine TGF-beta
  2. 3. ___ B is released by killer T cells to induces apoptosis
  3. 4. T cells mature in ___
  4. 6. Initial activation of T and B cells requires ___ steps
  5. 8. ___ proteins on T cells become increasingly sensitive after activations
  6. 10. The immune system develops ___ to avoid attacking healthy cells
  7. 11. B cell protein that binds to CD40L on T cells
  8. 13. Term for the killing of T cells that have been reactivated too many times
  9. 14. Th_ Th cells release TNF, IFN-gamma and IL-2
  10. 15. Forms pores in cell membranes of targets
  11. 17. Class II MHC molecules are only made by ___s
  12. 19. ___ T cells release cytokines to activate other immune cells
  13. 20. Type of lymphocytes created after initial exposure
  14. 21. Th cells activated in Peyer's patches become ___s
  15. 22. ___ T and B cells have not yet encountered their cognate antigen
  16. 23. Th_ Th cells release IL-4, IL-5 and IL-13
  17. 25. Class I MHC molecules are made by ___ body cells