Exam 2 Study Guide (Lecture 8)

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Across
  1. 7. Which CD4+ T cells can dampen the immune response?
  2. 8. One area of our bodies where iTregs play an incredibly important role.
  3. 10. The protein on the surface of target cells.
  4. 11. What do naïve T cells circulate through when trying to find their particular antigen on display?
  5. 14. What are both CTLA-4 and PD-1 molecules considered?
  6. 15. TGF-b reduces what type of rate in T cells and makes killer T cells less vicious killers?
Down
  1. 1. What molecule helps to terminate the immune response by inhibiting proliferation of previously activated T cells?
  2. 2. IL-10 blocks co-stimulatory signals and creates difficulties for APCs that are trying to activate what types of cells?
  3. 3. This process occurs in order for our bodies to rid themselves of obsolete T cells after they have been re-stimulated too many times.
  4. 4. Early during an infection, B7 will bind with CD28 and act as a what?
  5. 5. The protein on the surface of CTLs.
  6. 6. Ligation of CTLA-4 by B7 proteins acts as a what?
  7. 9. What are iTregs thought to inhibit in allergies?
  8. 12. What are IL-10 and TGF-b?
  9. 13. B7 proteins bind with this receptor and together they act as a signal dampener. It functions to make reactivation of T cells less efficient.