Exam 4 Crossword

3. A tumor that contains tissues derived from all three embryonic germ layers.
4. Event most associated with the Gene activation of oncogenes in cancer cells.
6. Protective benefit with regards to tumor formation.
8. Term for the wide variation in cell size observed in tumor cells.
9. An increase in the number of cells in an organ or tissue, which can lead to enlargement.
11. A process that describes the stages where a tumor becomes increasingly malignant, involving genetic and epigenetic changes.
14. A benign tumor that originates from fibrous connective tissue.
16. What type of carcinoma is most frequently associated with humoral hypercalcemia of malignancy.
18. A rare, cancerous bone tumor made up of cartilage cells.
19. Process by which the immune system recognizes and eliminates tumor cells.
20. A benign growth on the skin that results from the clustering of melanocytes, the pigment-producing cells.
22. Component of the tumor microenvironment that is responsible for synthesizing collagen.
23. Metastasis by which tumor cells spread via blood vessels.
24. Another word for Choristoma.
25. Abnormal cell growth within a tissue or organ.
26. Term that refers to normal mature tissue located in an abnormal location.

1. The development of secondary malignant growths at a distance from a primary site of cancer.
2. When cancer cells directly invade adjacent tissues.
5. Neoplastic transformation, that initiates the irreversible genetic change in a normal cell.
7. The loss of cellular differentiation and reversion to a more primitive cellular morphology.
10. The spread of cancer cells across the serosal cavities, such as the peritoneal cavity.
11. Genes that repair DNA damage.
12. Term for a preinvasive form of carcinoma that remains within the original epithelial structure.
13. Cellular process directly inhibited by the loss of cadherins in tumor cells during metastasis.
15. The embryonic germ layer that mesenchymal tumors originate.
17. Occurs similar to angiogenesis and is a response to growth factors like VEGF.
21. A cellular process characterized by irreversible genetic changes rendering cells unresponsive to typical growth controls.