Across
- 3. a special cytokine used to direct cells to their proper positions
- 8. a cell that crowns a Peyers patch and which specializes in sampling antigen from the intestine
- 10. the process during which a cell commits suicide in response to problems within the cell or to signals from outside the cell
- 12. a multi-protein complex in the cell that chops up proteins into small pieces
- 16. cell death typically caused by burns or other trauma. This type of cell death usually results in the contents of the cell being dumped into the tissues
- 17. a large, sack like structure inside the cell from which most proteins destined for transport to the cell surface begin their journey
- 18. an unlawful use of the class I display
- 19. to render nonfunctional
- 20. proteins such as CTLA-4 and PD-1 which help turn off the immune system once an invasion has been repulsed
Down
- 1. the clustering of TCRs and adhesion molecules at the point of contact between an APC and a T cell result in this formation
- 2. a cell found in the medulla of the thymus which tests for tolerance of self antigens
- 4. the idea that the increased incidence of allergies is due, at least in part, to improved hygiene
- 5. the process by which B cells in the bone marrow can "draw again from the deck" to try to make a BCR that is not self-reactive
- 6. synonym for central tolerance induction. The deletion of T cells whose receptors recognize MHC self peptide complexes in the thymic medulla
- 7. the process by which T cells with receptors that recognize abundant self antigens in the thymus are anergized or deleted
- 9. a starfish shaped cell which when activated by battle signals, travels from the tissues to the secondary lymphoid organs to activate naive T cells
- 11. a synonym for MHC restriction
- 13. a vaccine component included to increase its potency
- 14. a protein on the surface of a target cell which, when ligated by a Fasl protein on a killer cell, can instruct the target cell to commit suicide
- 15. a process by which starved cells recycle their components
