exam review

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Across
  1. 3. a special cytokine used to direct cells to their proper positions
  2. 8. a cell that crowns a Peyers patch and which specializes in sampling antigen from the intestine
  3. 10. the process during which a cell commits suicide in response to problems within the cell or to signals from outside the cell
  4. 12. a multi-protein complex in the cell that chops up proteins into small pieces
  5. 16. cell death typically caused by burns or other trauma. This type of cell death usually results in the contents of the cell being dumped into the tissues
  6. 17. a large, sack like structure inside the cell from which most proteins destined for transport to the cell surface begin their journey
  7. 18. an unlawful use of the class I display
  8. 19. to render nonfunctional
  9. 20. proteins such as CTLA-4 and PD-1 which help turn off the immune system once an invasion has been repulsed
Down
  1. 1. the clustering of TCRs and adhesion molecules at the point of contact between an APC and a T cell result in this formation
  2. 2. a cell found in the medulla of the thymus which tests for tolerance of self antigens
  3. 4. the idea that the increased incidence of allergies is due, at least in part, to improved hygiene
  4. 5. the process by which B cells in the bone marrow can "draw again from the deck" to try to make a BCR that is not self-reactive
  5. 6. synonym for central tolerance induction. The deletion of T cells whose receptors recognize MHC self peptide complexes in the thymic medulla
  6. 7. the process by which T cells with receptors that recognize abundant self antigens in the thymus are anergized or deleted
  7. 9. a starfish shaped cell which when activated by battle signals, travels from the tissues to the secondary lymphoid organs to activate naive T cells
  8. 11. a synonym for MHC restriction
  9. 13. a vaccine component included to increase its potency
  10. 14. a protein on the surface of a target cell which, when ligated by a Fasl protein on a killer cell, can instruct the target cell to commit suicide
  11. 15. a process by which starved cells recycle their components