Excitable Tissue - Neurons

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Across
  1. 3. an intracellular potential at which the net flow of ions is zero in spite of a concentration gradient and permeability
  2. 5. process at synapses by which a chemical signal (a transmitter) is released from one neuron and diffuses to other neurons or target cells where it generates a signal which excites, inhibits or modulates cellular activity.
  3. 10. K conc inside cell
  4. 12. Na conc outside cell
  5. 14. occurs when multiple subthreshold EPSPs from one neuron occur close enough in time to combine and trigger an action potential at the axon hillock
  6. 15. electrical charge (Hyperpolarisation) in the membrane of a postsynaptic neuron caused by the binding of an inhibitory neurotransmitter from a presynaptic cell to a postsynaptic receptor; makes it more difficult for a postsynaptic neuron to generate an action potential.
  7. 17. transmembrane proteins of excitable cells, that allow a flux of ions to pass only under defined circumstances
  8. 19. Action potentials are normally initiated at a low threshold "trigger zone" that is more excitable than any other part of the soma or dendrites. This trigger zone is located at the axon initial segment, the axon hillock (which contains the highest density of Na+-VGCs).
  9. 20. 60mV
  10. 21. a sudden, fast, transitory, and propagating change of the resting membrane potential
  11. 22. each action potential is a...
Down
  1. 1. when progressively larger numbers of primary afferent (presynaptic) neurons are activated simultaneously, until sufficient neurotransmitter is released to activate an action potential in the spinal cord (postsynaptic) neuron.
  2. 2. Na conc inside cell
  3. 4. a synaptic connection between the terminal end of a motor nerve and a muscle (skeletal/ smooth/ cardiac). It is the site for the transmission of action potential from nerve to the muscle synaptic connection between the terminal end of a motor nerve and a muscle (skeletal/ smooth/ cardiac). It is the site for the transmission of action potential from nerve to the muscle
  4. 6. Those axons which are not protected by myelin sheath
  5. 7. determined by the uneven distribution of ions (charged particles) between the inside and the outside of the cell, and by the different permeability of the membrane to different types of ions.
  6. 8. ntegral membrane proteins that change conformation in response to depolarization of the membrane potential, open a transmembrane pore, and conduct sodium ions inward to initiate and propagate action potentials
  7. 9. ensheathed along their entire length.
  8. 11. temporary depolarization of postsynaptic membrane caused by the flow of positively charged ions into the postsynaptic cell as a result of opening of ligand-sensitive channels.
  9. 13. K conc outside cell
  10. 16. open in resting neurons
  11. 18. -80mV