Extracellular matrix (ECM)

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Across
  1. 6. major cellular receptors for extracellular matrix proteins.
  2. 8. Abnormality in structure of basement membrane and lamina densa.
  3. 9. initiates degradation of collagen.
  4. 10. proteins that contain covalently linked glycosaminoglycans.
  5. 11. contains a long strand of hyaluronic acid to which link proteins are attached noncovalently.
  6. 14. a high molecular glycoprotein.
Down
  1. 1. A group of genetic disorders in which biosynthesis of type I collagen is defective.
  2. 2. Heterogeneous group of genetic disorders characterized by stretchy skin and loose joints.
  3. 3. oxidative deamination of LYS with the participation of oxidases and subsequent intermolecular condensation of 4-aldehyde groups take place,which forms a special type intermolecular cross-links
  4. 4. complex heteropolysaccharides constructed from repeat disaccharide units.
  5. 5. Inhibits elastase.
  6. 7. Heritable disease in which glycosylation of collagen is impaired and the skin blisters.
  7. 8. In absence of this organic compound the melting temperature of collagen drops.
  8. 12. Major glycoproteins of connective tissues and provide tensile strength.
  9. 13. a fibrous insoluble protein that is present in the aorta, lungs and ligaments.