Across
- 2. breeding objectives based mostly on ___________ concerns rather than health/welfare/purpose of the animal.
- 3. deomestic cats spread along trade routes – ______ attracted mice attracted cats.
- 5. can more easily (or just as easily) predict the phenotype of _________ offspring cf purebred offspring.
- 6. gene expression in the ______________ of domestic dogs is very different cf grey wolves – behavioural modifications.
- 7. __________________ disease states such as hip dysplasia can be objectively quantified.
- 10. all domestic cats originated exclusively from _____ of the six species of wildcat – F silvestris lybica.
- 11. __________ ____ principles should be used to introduce new genetic material – eg getting non hip dysplasia gene from greyhound into Labrador, after third backcross, looks like lab, but no HD.
- 13. in a review of the top 50 dog breeds, at least every one of them had an aspect of their _____________ predisposing to a disorder eg fine legs of mini poodle – fractures. However, better info on prevalence needed.
- 14. the ____________ ____________ and Labrador were the top two in the most common 50 dog breeds for having the most inherited autosomal recessive disorders – but we don’t know the prevelance!
- 16. unfortunately, there is little/no use of ______ (abbreviation for best linear unbiased prediction) or index selections. Need to have a clearer selection criteria for non-visual traits (temperament etc)
- 17. in the last 200 _________, dog and cat breeds have been massively developed. Though relatively little selective breeding pressure on cats.
- 19. domestic cats are still genetically _________ from Middle Eastern wildcats (F sylvestris lybica) – less initial genetic variation than domestic dogs.
- 20. crossbreeding of dogs (and selling neutered offspring) has incredible potential to exploit __________.
Down
- 1. breed standards can encourage to select for anatomical and ________________ problems.
- 4. in dogs, the most commonly affected organ system by autosomal recessive disorders in the top 50 common dog breeds is the _________ __________.
- 6. a few breeds eg manx cat, Scottish fold cat, merle dog, have been founded on _____________ for a defective gene – this is wrong!!
- 8. in the top 50 common dog breeds, 312 disorders were identified, 78% of which were inherited by ____________ _____________ pattern. Need info on prevalence.
- 9. inbreeding _____________ are high in rare breeds of dogs and cats. In more common dog breeds inbreeding not as much of a problem (unless overuse of top sires or linebreeding occurs)
- 12. dogs originated exclusively from _____ _________.
- 13. a _____________ change of dog breeders/showers/buyers is required – this is not easy!
- 15. grey wolf populations were many, and had many back crossings – large amount of genetic ________ plus a long period for genetic mutations to accumulate has led to the variation in dog breeds we see today.
- 18. genetically, dog breeds fall into four distinct groupings – asian/ancient, _________, hunting, mastiff.