Fatty Acid Biosynthesis

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Across
  1. 4. The role of this molecule is to carry the growing fatty acid chain
  2. 7. The end product of a complete fatty acid synthesis cycle
  3. 12. What is the product of the condensation step in fatty acid synthesis?
  4. 13. Delta9 desaturase enzyme catalyze the conversion of stearic acid into ______
  5. 14. Double bond is introduced by oxidation reaction catalyzed by _______ enzyme
  6. 15. Enzyme that converts acetyl-CoA to malonyl-CoA
  7. 19. Location where fatty acid synthesis is especially active in humans
  8. 20. ACP, like CoA both contains _______ group that forms a thioester with an acyl group
Down
  1. 1. Can be ynthesized by plants but not by humans
  2. 2. What is the source of the two carbons used in fatty acid synthesis?
  3. 3. The conversion of acetoacetyl-ACP to hydroxybutyryl-ACP requires ____ as a reactant
  4. 5. The transport of an acyl carnitine from cytosol to mitochondrial matrix is directly coupled to the transport of a ____
  5. 6. Hormone that promotes the activation of acetyl-CoA carboxylase
  6. 8. In this reaction, a bicarbonate ion is loaded on the biotin prosthetic group attached to ACC
  7. 9. Acetyl-CoA enters the cytosol in the form of _____
  8. 10. This enzyme presents in both mitochondria and endoplasmic reticulum
  9. 11. This multienzyme complex catalyzes addition of two carbon units )from malonyl-CoA)
  10. 16. Acetyl CoA carboxylase has a covalently bound prosthetic group called _________
  11. 17. How many cycles required to form palmitoyl-CoA?
  12. 18. Where does the majority of fatty acid synthesis take place?