Fill the crossword below comprising of contents covered in Pharmacology (30 marks)

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Across
  1. 2. Percentage of the drug dosage that is absorbed.
  2. 9. are proteins that help speed up metabolism, or the chemical reactions in our bodies. They build some substances and break others down.
  3. 10. his studies led to the discovery of penicillin and its curative effect in various infectious diseases
  4. 11. are macromolecules involved in chemical signaling between and within cells; they may be located on the cell surface membrane or within the cytoplasm
  5. 12. Suffix denoting killing, as of microorganisms.
  6. 14. Antibiotic that kills bacteria; chemical that kills or destroys bacteria.
  7. 15. the lowest concentration of an antibiotic at which bacterial growth is completely inhibited.
  8. 16. are substances that cause harmful, dangerous or fatal symptoms in living substances.
  9. 19. These are drugs whose side effects include nephrotoxicity and ototoxicity
  10. 21. This refers to the use of natural metabolites, hormones or their congeners in deficiency states, e.g. levodopa in parkinsonism, insulin in diabetes mellitus
  11. 24. Use of antibiotics to prevent infection, usually before a surgical procedure or in patients at risk for infection.
  12. 25. are integral membrane proteins that play a critical role in drug disposition by affecting absorption, distribution, and excretion.
  13. 26. is a molecule capable of binding to and functionally activating a target
  14. 27. Chemical substance that produces a change in body function
  15. 28. Study of the absorption, distribution metabolism and excretion (ADME) of drugs (“i.e what the body does to the drug”).
  16. 29. Use of drugs to inhibit the growth of or to destroy infectious organisms or cancer cells; use of drugs to kill or inhibit the growth of infectious organisms or cancer cells
  17. 30. Chemical that inhibits growth or reproduction of bacteria but does not kill bacteria; antibiotic that inhibits the growth of, but does not kill, bacteria.
Down
  1. 1. is another name for metabolism.
  2. 3. It’s the effect of drugs upon microorganisms, parasites and neoplastic cells living and multiplying in living organisms.
  3. 4. is the area of pharmacology that focuses on the method for achieving effective drug administration.
  4. 5. Mental state characterized by depressed mood, with feelings of frustration and hopelessness.
  5. 6. his studies led to the discovery of streptomycin, a new antibiotic.
  6. 7. Antibacterial drugs obtained by chemical synthesis and not from other microorganisms.
  7. 8. The study of the biological and therapeutic effects of drugs (i.e,“what the drug does to the body”).
  8. 13. It deals with the proper selection and use of drugs for the prevention and treatment of disease.
  9. 17. It refers to selective enhancement of the level of activity of specialized cells, e.g. adrenaline stimulates heart, pilocarpine stimulates salivary glands
  10. 18. is a molecule that binds to a target and prevents other molecules (e.g., agonists) from binding
  11. 20. Substance that kills disease-causing microorganisms on nonliving surfaces
  12. 22. An official code containing a selected list of the established drugs and medical preparations with descriptions of their physical properties and tests for their identity, purity and potency
  13. 23. It’s the science of poisons. Many drugs in larger doses may act as poisons.