FOM II: Unit 3 Genetics

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Across
  1. 2. This marker is high in Down's syndrome & low in Edward's syndrome
  2. 4. Nondisjunction in Meiosis II can cause this type of disomy
  3. 5. ASO involves hybridization of these fluorescent-labeled molecules
  4. 7. This dominant X-linked syndrome is male neonatal lethal
  5. 8. Syndrome associated with Trisomy 13
  6. 9. Name of Chromosome 14 & 21 translocation
  7. 12. This chromosome created by a translocation between 9 & 22 is associated with chronic myeloid leukemia
  8. 13. A disease becomes more severe with successive generations
  9. 14. Effect increases the frequency of a rare allele in a sub-population
  10. 15. A mutation in fibrillin can cause this autosomal dominant syndrome
Down
  1. 1. Autosomal recessive condition caused by deficiency in phenylalanine hydroxylase
  2. 3. This gene is involved in the inactivation of the X chromosome
  3. 6. Genetically different mitochondria within one individual or cell
  4. 10. The EcoR1 endonuclease recognizes this type of sequence to cleave DNA
  5. 11. Calculated in the equation 2(cMZ-cDZ)
  6. 13. This marker is high in Spinal Bifida defects