Fungus

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Across
  1. 1. bipyramidal crystals derived from eosinophils in allergic fungal mucin
  2. 2. stain that highlights fungal elements in tissue sections
  3. 4. oral appearance of histoplasmosis with nonhealing ulceration
  4. 6. clinical white plaque mimic of chronic hyperplastic candidiasis
  5. 7. pathway of spread for severe sinonasal mucormycosis into orbit and brain
  6. 10. right angle branching pattern typical of mucormycosis histology
  7. 11. descriptive nickname for broad based budding yeast of blastomycosis
  8. 14. key feature distinguishing thrush from leukoplakia
  9. 17. differential for median rhomboid glossitis not limited to midline
  10. 18. hallmark clinical progression of midfacial mucormycosis with black eschar
  11. 19. most common invasive mold infection in immunocompromised hosts
  12. 21. inflammatory cells abundant in allergic fungal sinusitis material
  13. 22. silver stain commonly used to confirm deep fungal infections in biopsy
  14. 23. erythematous candidiasis under a removable prosthesis often from continuous wear or poor hygiene
  15. 24. fungus ball radiopacity often filling a paranasal sinus cavity
  16. 26. septation feature distinguishing aspergillus from mucorales
  17. 28. common cutaneous manifestation of candidiasis in infants
  18. 30. dryness that predisposes to erythematous candidiasis and hairy tongue changes
  19. 31. common environmental reservoir for histoplasma spores
  20. 33. endemic region for histoplasmosis exposure
  21. 35. common mucorales genus implicated in rhino orbital cerebral disease
  22. 38. orderly acute angle branching pattern of aspergillus hyphae
  23. 39. site commonly involved by candidiasis in immunocompromised hosts
  24. 41. palatal counterpart to midline tongue patch in median rhomboid glossitis
  25. 42. growth as hyphae at room temperature and as yeasts at body temperature
  26. 46. classic thrush with wipeable white plaques revealing erythematous base
  27. 47. broad ribbonlike hyphae lacking septa seen in mucorales
  28. 48. midline dorsal tongue patch sometimes with kissing palate lesion
  29. 49. aggressive disease in profoundly immunosuppressed patients often fatal without rapid therapy
Down
  1. 1. rare nonscrapable white plaque that mimics leukoplakia requires biopsy
  2. 3. noninvasive aspergillus disease causing chronic rhinosinusitis with allergic mucin
  3. 5. risk factor for stomatitis and for angular cheilitis in older adults
  4. 8. species most often responsible for oral candidiasis
  5. 9. deep infection that can occur in immunocompetent patients and mimic squamous cell carcinoma
  6. 12. covid era risk factor associated with mucormycosis surges
  7. 13. red sore burning mouth often after broad spectrum antibiotics or with dry mouth
  8. 15. tendency of deep fungal oral lesions to resemble malignancy clinically
  9. 16. medication exposure that frequently precedes erythematous candidiasis
  10. 20. metabolic state in type 1 diabetes that markedly increases mucor risk
  11. 25. deep mycosis from spore laden dust associated with bird or bat droppings
  12. 27. key differential for angular cheilitis along lip border
  13. 29. essential first step to confirm suspected deep fungal lesions and distinguish lookalikes
  14. 32. scenarios after which mucormycosis incidence historically rises
  15. 34. angioinvasive black fungus infection causing tissue infarction and necrosis
  16. 36. patients at highest risk for invasive fungal disease (e.g., transplant, HIV, chemo)
  17. 37. fissuring and erythema at commissures often due to excess moisture with candida
  18. 40. invasion and thrombosis of blood vessels explaining rapid tissue ischemia in mucormycosis
  19. 43. another reservoir linked to cave and old building exposure
  20. 44. elongated filiform keratin no depapillation some keratin wipes off not a candidiasis
  21. 45. most common surface opportunistic infection of oral mucosa genitalia and skin