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Across
  1. 2. The massive molecular ....... responsible for synthesizing the new RNA strand
  2. 3. The primary protein complex that acts as a ....... for the assembly of the preinitiation complex
  3. 4. BOX An essential guide or sequence used by the leader to locate the genes coordinates
  4. 7. The biochemical process of copying genetic info from a DNA ....... into an RNA strand
  5. 8. A saddle shaped protein that sits on the DNA minor groove to start the building process
Down
  1. 1. The drastic 80 degree bending of the DNA helix that occurs after TBP binds
  2. 5. The mechanical tool used by TFIIH to "unzip" or break open the DNA double helix
  3. 6. The specific DNA region where the "team" assembles to determine the direction of transcription